Incidence of SARS-CoV-2 re-infection in anti-nucleocapsid IgG-positive healthcare workers: a prospective cohort studyArticle Published on 2023-04-012023-07-08 Journal: Irish Journal of Medical Science [Category] COVID19(2023년), [키워드] anti-nucleocapsid antibody Healthcare workers incidence Re-infection SARS-CoV-2. [DOI] 10.1007/s11845-022-02997-w PMC 바로가기
A 1-year longitudinal study on COVID-19 convalescents reveals persistence of anti-SARS-CoV-2 humoral and cellular immunityCOVID-19 회복기에 대한 1년 종단 연구는 항 SARS-CoV-2 체액성 및 세포성 면역의 지속성을 보여줍니다Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 1-year after infection anti-SARS-CoV-2 humoral antibody antibody durability. caused CD4 CD8 CD8 T cell CD8 T cell responses Cell cellular immunity central memory circulating antibodies circulating antibody Cohort convalescent COVID-19 COVID-19 convalescent COVID-19 patient disease disease severity effective IgG level immune Immune components immune memory immune protection Immunity induce Infection information Kinetics maintain memory memory B memory B cell Memory responses memory T cells omicron Omicron variant peptide peptide pool persistence protective immunity provide RBD IgG Re-infection recorded response reveal SARS-CoV-2 SARS-CoV-2 circulating antibodies SARS-COV-2 infection subject Symptom T cell T cell response T cell responses T cells tested the RBD the SARS-CoV-2 variant [DOI] 10.1080/22221751.2022.2049984 PMC 바로가기 [Article Type] Article
Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in childrenArticle Published on 2022-10-192022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome analyzed anti-S IgG antibody Antigen antigen specific antibody Asymptomatic cause children collected coronavirus cross-react cross-reactive cross-reactive antibody exhibit HCoV-OC43 Hospitalization Humoral immunity IgG antibody Infection low pathogenic human coronaviruses median age mild symptoms Mutant SARS-CoV-2 Neutralizing activity neutralizing activity. neutralizing antibody nucleocapsid occurred outbreak pathogenic pathogenic human coronavirus question Re-infection reached Receptor binding domain SARS-CoV-2 seropositive sample serum sample Seven SRAS-CoV-2 These data wild-type [DOI] 10.3389/fimmu.2022.1042406 PMC 바로가기
Outcome of SARS-CoV-2 infection among patients with common variable immunodeficiency and a matched control group: A Danish nationwide cohort studyArticle Published on 2022-09-232022-11-16 Journal: Frontiers in Immunology [Category] SARS, 치료기술, [키워드] age calculate Clinical outcome cohort study common variable immunodeficiency (CVID) conducted Contact control group Coronavirus-2 Course COVID-19 Cox regression CVID death detectable estimate Gender General population groups hospital Immunity immunodeficiency in both groups inborn errors of immunity (IEI) incidence rate increased risk individual Infection mechanical ventilation not differ Novel coronavirus outcome Patient Re-infection risk Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severe adult respiratory coronavirus-2 (SARS-CoV-2) severe novel coronavirus 2019 (COVID-19). severity the timing was used [DOI] 10.3389/fimmu.2022.994253 PMC 바로가기
Homotypic and heterotypic immune responses to Omicron variant in immunocompromised patients in diverse clinical settings다양한 임상 환경에서 면역 저하 환자의 오미크론 변이체에 대한 동형 및 이형 면역 반응Article Published on 2022-08-042022-09-11 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료법, [키워드] CD4 CD8 Cellular immune response clinical setting comparable controls cross-neutralization D614G Delta Delta variants disease severity dose Host humoral identify immune immune response immune responses Immunocompromised Immunocompromised patient Immunocompromised patients implication Infection magnitude neutralization neutralizing antibody omicron Organ transplant Patient patients peptide peptide pools Pseudovirus neutralization assay Re-infection recipient response responses risk of infection SARS-CoV-2 severe COVID-19 subset T-cell Response T-cell responses uninfected Vaccine variant variants [DOI] 10.1038/s41467-022-32235-x PMC 바로가기 [Article Type] Article
Response to Letters regarding “Re-infection with SARS-CoV-2 in solid-organ transplant (SOT) recipients: Incidence density and convalescent immunity prior to re-infection”Comment Published on 2022-08-012023-07-09 Journal: Transplant infectious disease : an official journa [Category] COVID19(2023년), [키워드] Re-infection SARS-CoV-2 solid organ transplant. [DOI] 10.1111/tid.13870 PMC 바로가기 [Article Type] Comment
Real-life data on monoclonal antibodies and antiviral drugs in Italian inborn errors of immunity patients during COVID-19 pandemic코로나19 팬데믹 기간 동안 이탈리아 선천성 면역질환 환자의 단클론항체 및 항바이러스제 실생활 데이터Article Published on 2022-07-282022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Alpha Analysis Antiviral antiviral agent Antiviral agents antiviral drug antiviral drugs Asymptomatic Care circulating Cohort contributed Course COVID-19 COVID-19 pandemic COVID-19 severity disease disease severity duration of viral shedding Effect Efficacy error evaluated Hospital admission Hospitalization hospitalization-risk hospitalizations hospitalized patients ICU admission Immunity immunized Inborn Inborn errors inborn errors of immunity Infection Italian longitudinal lower risk mAbs mitigate monoclonal monoclonal antibodies monoclonal antibody Mortality mRNA vaccine mRNA vaccines offered Patient patients treated performed positive Prevent prophylactic measure prophylactic measures Re-infection Re-infections reduce reduced Reinfection reinfection. reported respond risk Safe SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positivity SARS-CoV-2 strains SARS-CoV-2 virus severe COVID-19 severe disease Spectrum Spread Strains therapeutic therapy treated vaccination Vaccinations Viral viral shedding viral strain viral strains widespread [DOI] 10.3389/fimmu.2022.947174 PMC 바로가기 [Article Type] Article
Kinetics of anti-nucleocapsid IgG response in COVID-19 immunocompetent convalescent patientsCOVID-19 면역적격 회복기 환자에서 항뉴클레오캡시드 IgG 반응의 동역학Article Published on 2022-07-202022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] absence anti-Nucleocapsid IgG anti-SARS-CoV-2 anti-SARS-CoV-2 humoral antibody Antibody Response Antibody testing BMI comprehension convalescent patient Convalescent patients country COVID-19 COVID-19 convalescent patient COVID-19 disease decrease detectable develop disease severity humoral humoral immune response IgG IgG antibodies IgG antibody immunodeficiency inclusion criteria Kinetics knowledge longitudinal study majority Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nucleocapsid Patient positive Protein Re-infection robust RT- PCR SARS-CoV-2 SARS-CoV-2 nucleocapsid serum Sex Treatment Vaccination strategies Vaccination strategy virus infection [DOI] 10.1038/s41598-022-16402-0 PMC 바로가기 [Article Type] Article
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineagesSARS-CoV-2 오미크론 하위 계통의 기원, 바이러스학적 특징, 면역 회피 및 개입Review Published on 2022-07-192022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] Coronavirus, COVID19(2023년), SARS, 변종, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.1.529 benefit breakthrough infections carried caused circulating coronavirus dominant Features global public health Immune escape immune evasion Infection Intervention Mutation Neutralizing antibodies neutralizing antibody omicron Omicron variant origin other variant other variants Re-infection Re-infections SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus Spike protein Spread Therapeutics Transmissibility vaccination Vaccine variant variants Virological VOCs [DOI] 10.1038/s41392-022-01105-9 PMC 바로가기 [Article Type] Review
COVID-19 symptom severity predicts neutralizing antibody activity in a community-based serological studyCOVID-19 증상 중증도는 커뮤니티 기반 혈청 연구에서 중화 항체 활성을 예측합니다Article Published on 2022-07-182022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료법, [키워드] analyzed association blood sample Blood samples Community-based cohort conducted COVID-19 symptom demonstrated detectable General population highlight IgG antibodies immune response individual Infection information less magnitude measure NAb activity nAb response NAbs Neutralizing antibodies neutralizing antibody populations positive positive relationship predict protective immunity provide Re-infection Research SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody serological Serological testing seropositive participant seropositive participants severity Symptom symptom severity vaccination Variation Virus neutralization [DOI] 10.1038/s41598-022-15791-6 PMC 바로가기 [Article Type] Article